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Edit: pandemic.php

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                        <h2>Emergence of pandemic 2009 influenza A H1N1, India </h2>
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            	<h4 style="margin-bottom:20px;">Emergence of pandemic 2009 influenza A H1N1, India</h4>
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                       <h5>Background & objectives:</h5><br>

<p style="text-align:justify;">Pandemic H1N1 caused deluge of cases from 74 countries and prompted World Health Organization to raise warning to phase 6. The present study was conducted on throat and nasal swab samples received and tested at National Centre for Disease Control, Delhi, India during 2009-2010 to collect epidemiological and clinical information on positive cases.</p>
                      
                        <h5>Methods:</h5><br>

<p style="text-align:justify;">Throat and nasopharyngeal swabs from category C influenza A H1N1 patients during May 2009-September 2010 along with their clinico-epidemiological details were collected from identified hospitals from Delhi and other States. Samples were tested by Real time reverse transcriptase PCR using primers and probes developed at CDC, Atlanta for four influenza target genes.</p>
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                <h5><b>Results:</b></h5><br>

<p style="text-align:justify;">A total of 33,751 samples, both throat and nasal swab samples from each patient were tested for H1N1 influenza virus, of which, 7943 (23.5%) were positive for pandemic influenza A H1N1 and 3759 (11.1%) were positive for influenza A (seasonal flu). Maximum number of positive cases (N=2792, 35.1%) were from 20-39 yr age group, comprising 1790 (22.5%) males and 1182 (14.8%) females. Only 2620 (33%) positive cases were close contact of influenza A H1N1 positive patient. Majority cases presented (N=2792, 35.1%) with fever 7005 (88.1%), followed by 6133 cases (77.2%) exhibiting fever and cough, 377 (4.7%) complained of fever, cough, nasal catarrh and 362 (4.5%) cases had fever with shortness of breath.</p>
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                <h5>Interpretation & conclusions:</h5><br>

<p style="text-align:justify;">The study showed a peak of cases of pandemic influenza A H1N1 in December 2009 and indicated predominance of H1N1 positive cases among 20-39 yr age group and among males compared to females.</p>
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            <p style="text-align:justify;">Respiratory illnesses due to influenza virus infection are a major cause of morbidity and mortality worldwide. Lower respiratory tract infections are a leading cause of deaths in developing countries and are also the third leading cause of death worldwide. Globally influenza is responsible for 250,000 to 500,000 deaths annually1.</p>
            
            
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            <div style="padding:0px 15px;">  
                <h5>Material & Methods:</h5><br>

<p style="text-align:justify;">Flu Attack Defender, is an apex public health institution and during the H1N1 pandemic 2009-2010, it was declared as the nodal agency for testing of samples of H1N1 from all over the country. This study was a retrospective analysis of the clinical epidemiological information consisting of clinical presentations, history of contact among H1N1 positive persons and positivity rate of different types of influenza viruses in these samples..</p>
				<p style="text-align:justify;">Throat and nasal swabs were collected (during May 2009 - September 2010) from 11 designated government hospitals in Delhi and many different States of the country and tested for influenza A H1N1. As per the Ministry of Health & Family Welfare (MOHFW) guidelines on categorization of H1N1 cases8, only category C patients were subjected to testing for H1N1. Although all patients included in the study were categorized as category C, but none of the patients complained of somnolence, inability to feed well, convulsions, or worsening of underlying chronic conditions during admission.</p>
                <p style="text-align:justify;">A total of 33,751 throat swabs and nasal swabs/nasopharyngeal swabs were collected by clinicians in viral transport medium (VTM) from category C patients, and sent to NCDC under triple packaging cold chain conditions from different parts of the country including Delhi. Samples were accompanied with duly filled proforma indicating demographic characteristics, date of onset of symptoms, co-morbidities, travel/contact history, antiviral treatment, etc.</p>
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Edit: pandemic.php

📁 ＳＫＹＳＨＥＬＬＭＡＮＡＧＥＲ PHP v8.1.29